Despite effective antiviral therapies, the risk for hepatocellular carcinoma is not eliminated following viral cure of an HCV infection. This new publication sheds light on the role of HCV-induced persistent epigenetic changes in liver cancer risk. This research highlights the value of epigenomic analysis for earlier detection and improved management of hepatocellular carcinoma.
HCV-induced epigenetic changes associated with liver cancer risk persist after sustained virologic response. Hamdane N. et al. Gastroenterology. 2019 Jun;156(8):2313-2329.e7.
The paper can be accessed freely here.
Find the press release here.